《英文msh詞典》gp120 v fms
[入口詞] gp120 v fms
[主題詞] Oncogene Protein gp140(v-fms)
[英文釋義] Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences,which,in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor),normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).